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ContextIn their first year of postgraduate training, interns commonly work shifts that are longer than 24 hours. Extended-duration work shifts are associated with increased risks of automobile crash, particularly during a commute from work. Interns may be at risk for other occupation-related injuries.ObjectiveTo assess the relationship between extended work duration and rates of percutaneous injuries in a diverse population of interns in the United States.Design, Setting, and ParticipantsNational prospective cohort study of 2737 of the estimated 18 447 interns in US postgraduate residency programs from July 2002 through May 2003. Each month, comprehensive Web-based surveys that asked about work schedules and the occurrence of percutaneous injuries in the previous month were sent to all participants. Case-crossover within-subjects analyses were performed.Main Outcome MeasuresComparisons of rates of …