作者
Chiatogu Onyewu, Floyd L Wormley Jr, John R Perfect, Joseph Heitman
发表日期
2004/12
期刊
Infection and immunity
卷号
72
期号
12
页码范围
7330-7333
出版商
American Society for Microbiology
简介
In Candida albicans, calcineurin is essential for virulence and survival during membrane perturbation by azoles. Crz1 is a proposed downstream target of calcineurin based on studies of Saccharomyces cerevisiae. However, the in vitro phenotypes of C. albicans crz1/crz1 and calcineurin mutants differ and Crz1 is not required for virulence.
引用总数
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