作者
Paul D Brown, Karla V Ballman, Teresa A Rummans, Matthew J Maurer, Jeff A Sloan, Bradley F Boeve, Lalit Gupta, David F Tang-Wai, Robert M Arusell, Matthew M Clark, Jan C Buckner
发表日期
2006/2
期刊
Journal of neuro-oncology
卷号
76
页码范围
283-291
出版商
Kluwer Academic Publishers
简介
Objective
To assess baseline quality of life (QOL) and its prognostic importance for adults with newly diagnosed high-grade gliomas, we analyzed QOL and outcome data prospectively collected in three phase II high-grade glioma protocols.
Methods
At study entry, patients completed five self-administered forms to assess overall QOL (linear analogue scale assessment [LASA] and Functional Assessment of Cancer Therapy-Brain [FACT-Br]); fatigue (Symptom Distress Scale [SDS]); excessive daytime somnolence (Epworth Sleepiness Scale [ESS]); and depression (POMS-SF). Folstein Mini-Mental State Examination (MMSE) and Eastern Cooperative Oncology Group (ECOG) performance scores (PS) were obtained by the health care provider.
Results
Baseline QOL data were available for 194 of 220 patients (88 …
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