作者
Jiachen Zhang, Onaizah Onaizah, Amir Sadri, Eric Diller
发表日期
2017/6/1
期刊
Biomedical microdevices
卷号
19
期号
2
页码范围
43
出版商
Springer US
简介
Cell sorters play important roles in biological and medical applications, such as cellular behavior study and disease diagnosis and therapy. This work presents a label-free microfluidic sorter that has a downstream-pointing magnetic elastic diverter. Different with most existing magnetic sorters, the proposed device does not require the target microobjects to be intrinsically magnetic or coated with magnetic particles, giving users more flexibility in sorting criteria. The diverter is wirelessly deformed by an applied magnetic field, and its deformation induces a fluid vortex that sorts incoming microobjects, e.g., cells, to the collection outlet. The diverter does not touch samples in this process, reducing the sample contamination and damage risks. This sorter uses a magnetic field generated by off-chip electromagnetic coils that are centimeters away from the device. With simple structure and no on-chip circuits or coils …
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