作者
Michael Marquis, Rachel I Wilson
发表日期
2022/12/19
期刊
Current Biology
卷号
32
期号
24
页码范围
5406-5414. e5
出版商
Elsevier
简介
The Drosophila brain contains about 50 distinct morphological types of dopamine neurons.1,2,3,4 Physiological studies of Drosophila dopamine neurons have been largely limited to one brain region, the mushroom body,5,6,7,8,9,10,11,12,13 where they are implicated in learning.14,15,16,17,18 By comparison, we know little about the physiology of other Drosophila dopamine neurons. Interestingly, a recent whole-brain imaging study found that dopamine neuron activity in several fly brain regions is correlated with locomotion.19 This is notable because many dopamine neurons in the rodent brain are also correlated with locomotion or other movements20,21,22,23,24,25,26,27,28,29,30; however, most rodent studies have focused on learned and rewarded behaviors, and few have investigated dopamine neuron activity during spontaneous (self-timed) movements. In this study, we monitored dopamine neurons in …
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