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In this era of aggressive organ recovery and transplantation, our human leukocyte antigen (HLA) laboratory recently (February 2009) crossmatched for a kidney and a liver from a deceased donor that were transplanted into a single patient. However, the kidney from the donor had been transplanted 7 months earlier into the patient who was now the donor. Although a few cases of kidney reuse (1–4) have been reported, this is the first report pointing out the potential need of a virtual crossmatch in cases of kidney reuse for HLA-sensitized candidates if cells from the kidney reuse donor are not available.