作者
Andrea Messori, Sabrina Trippoli, Paola Becagli, Gaetano Zaccara
发表日期
1999/8
期刊
Pharmacoeconomics
卷号
16
页码范围
153-163
出版商
Springer International Publishing
简介
Objective: In patients with amyotrophic lateral sclerosis, long term treatment with riluzole has been reported to improve survival or tracheostomy-free survival in comparison with placebo. We conducted a pharmacoeconomic analysis for estimating the cost per life-year gained using this drug.
Design: This study was an incremental cost-effectiveness lifetime analysis.
Setting: The clinical material was derived from 2 placebo-controlled randomized controlled trials comparing riluzole versus usual care without riluzole, which were identified through a literature search based on the IOWA and the Medline systems.
Patients and interventions: The study included 633 patients with amyotrophic lateral sclerosis. Patient-level information was retrieved from313 patients treated with riluzole and 320 patients assigned to placebo.
Survival after …
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A Messori, S Trippoli, P Becagli, G Zaccara - Pharmacoeconomics, 1999