作者
Paolo Spagnolo, Elisabetta Balestro, Stefano Aliberti, Elisabetta Cocconcelli, Davide Biondini, Giovanni Della Casa, Nicola Sverzellati, Toby M Maher
发表日期
2020/8/1
期刊
The Lancet Respiratory Medicine
卷号
8
期号
8
页码范围
750-752
出版商
Elsevier
简介
As of May 6, 2020, nearly 3· 7 million people have been infected and around 260 000 people have died from coronavirus disease 2019 (COVID-19) worldwide. 1 Almost all COVID-19-related serious consequences feature pneumonia. 2 In the first large series of hospitalised patients (n= 138) with COVID-19 in Wuhan, China, chest CT showed bilateral ground glass opacities with or without consolidation and with lower lobe predilection in all patients. 3 In this series, 36 (26%) patients required intensive care, of whom 22 (61%) developed acute respiratory distress syndrome (ARDS). 3 The mechanisms through which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes lung damage are only partly known, but plausible contributors include a cytokine release syndrome triggered by the viral antigen, drug-induced pulmonary toxicity, and high airway pressure and hyperoxia-induced acute lung injury …
引用总数
学术搜索中的文章
P Spagnolo, E Balestro, S Aliberti, E Cocconcelli… - The Lancet Respiratory Medicine, 2020