作者
Zengliang Jiang, Ting-yu Sun, Yan He, Wanglong Gou, Luo-shi-yuan Zuo, Yuanqing Fu, Zelei Miao, Menglei Shuai, Fengzhe Xu, Congmei Xiao, Yuhui Liang, Jiali Wang, Yisong Xu, Li-peng Jing, Wenhua Ling, Hongwei Zhou, Yu-ming Chen, Ju-Sheng Zheng
发表日期
2020/12
期刊
BMC medicine
卷号
18
页码范围
1-11
出版商
BioMed Central
简介
Background
Little is known about the inter-relationship among fruit and vegetable intake, gut microbiota and metabolites, and type 2 diabetes (T2D) in human prospective cohort study. The aim of the present study was to investigate the prospective association of fruit and vegetable intake with human gut microbiota and to examine the relationship between fruit and vegetable-related gut microbiota and their related metabolites with type 2 diabetes (T2D) risk.
Methods
This study included 1879 middle-age elderly Chinese adults from Guangzhou Nutrition and Health Study (GNHS). Baseline dietary information was collected using a validated food frequency questionnaire (2008–2013). Fecal samples were collected at follow-up (2015–2019) and analyzed for 16S rRNA sequencing and targeted fecal metabolomics. Blood samples were collected and …
学术搜索中的文章
Z Jiang, T Sun, Y He, W Gou, L Zuo, Y Fu, Z Miao… - BMC medicine, 2020