作者
Philip Zachariah, Katia C Halabi, Candace L Johnson, Susan Whitter, Jorge Sepulveda, Daniel A Green
发表日期
2020/10/15
期刊
Clinical Infectious Diseases
卷号
71
期号
16
页码范围
2305-2306
出版商
Oxford University Press
简介
To the Editor—Published data suggest lower rates of severe coronavirus disease 2019 (COVID-19) in pediatric age groups [1, 2]. However, the relative contribution of infants and children to community transmission is not known. Data from China suggest that children were infected early in the outbreak [3]. A report published in this journal described the presence of a high nasopharyngeal (NP) viral load of severe acute respiratory coronavirus 2 (SARS-CoV-2) in a well infant [4]. Whether this observation is generalizable to symptomatic infants, and how it compares to NP viral loads in older children and adolescents, is not known. Studies in adults have demonstrated a positive correlation between viral load and COVID-19 severity [5]. While some data have suggested a higher disease severity in infants [2, 6], how NP viral load correlates with severity across the pediatric age spectrum has not been firmly established …
引用总数
20202021202220232024911711
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