作者
Evan Wood, Loai Albarqouni, Stacey Tkachuk, Carolyn J Green, Keith Ahamad, Seonaid Nolan, Mark McLean, Jan Klimas
发表日期
2018/8/28
来源
Jama
卷号
320
期号
8
页码范围
825-833
出版商
American Medical Association
简介
Importance
Although severe alcohol withdrawal syndrome (SAWS) is associated with substantial morbidity and mortality, most at-risk patients will not develop this syndrome. Predicting its occurrence is important because the mortality rate is high when untreated.
Objective
To assess the accuracy and predictive value of symptoms and signs for identifying hospitalized patients at risk of SAWS, defined as delirium tremens, withdrawal seizure, or clinically diagnosed severe withdrawal.
Data Sources
MEDLINE and EMBASE (1946-January 2018) were searched for articles investigating symptoms and signs predictive of SAWS in adults. Reference lists of retrieved articles were also searched.
Study Selection
Original studies that were included compared symptoms, signs, and risk assessment tools among patients who developed SAWS and patients who did not.
Data Extraction and Synthesis
Data were extracted and used to …
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