作者
Aitor Blanco‐Míguez, Alberto Gutiérrez‐Jácome, Martín Pérez‐Pérez, Gael Pérez‐Rodríguez, Sandra Catalán‐García, Florentino Fdez‐Riverola, Anália Lourenço, Borja Sánchez
发表日期
2016/6
来源
Protein Science
卷号
25
期号
6
页码范围
1084-1095
简介
Chemoprevention is the use of natural and/or synthetic substances to block, reverse, or retard the process of carcinogenesis. In this field, the use of antitumor peptides is of interest as, (i) these molecules are small in size, (ii) they show good cell diffusion and permeability, (iii) they affect one or more specific molecular pathways involved in carcinogenesis, and (iv) they are not usually genotoxic. We have checked the Web of Science Database (23/11/2015) in order to collect papers reporting on bioactive peptide (1691 registers), which was further filtered searching terms such as “antiproliferative,” “antitumoral,” or “apoptosis” among others. Works reporting the amino acid sequence of an antiproliferative peptide were kept (60 registers), and this was complemented with the peptides included in CancerPPD, an extensive resource for antiproliferative peptides and proteins. Peptides were grouped according to one of the …
引用总数
201720182019202020212022202320244988178710
学术搜索中的文章
A Blanco‐Míguez, A Gutiérrez‐Jácome, M Pérez‐Pérez… - Protein Science, 2016