作者
Hooi-Ling Teoh, Shekeeb S Mohammad, Philip N Britton, Tejaswi Kandula, Michelle S Lorentzos, Robert Booy, Cheryl A Jones, William Rawlinson, Vidiya Ramachandran, Michael L Rodriguez, P Ian Andrews, Russell C Dale, Michelle A Farrar, Hugo Sampaio
发表日期
2016/3/1
期刊
JAMA neurology
卷号
73
期号
3
页码范围
300-307
出版商
American Medical Association
简介
Importance
Enterovirus 71 (EV71) causes a spectrum of neurological complications with significant morbidity and mortality. Further understanding of the characteristics of EV71-related neurological disease, factors related to outcome, and potential responsiveness to treatments is important in developing therapeutic guidelines.
Objective
To further characterize EV71-related neurological disease and neurological outcome in children.
Design, Setting, and Participants
Prospective 2-hospital (The Sydney Children’s Hospitals Network) inpatient study of 61 children with enterovirus-related neurological disease during a 2013 outbreak of EV71 in Sydney, Australia. The dates of our analysis were January 1, to June 30, 2013.
Main Outcomes and Measures
Clinical, neuroimaging, laboratory, and pathological characteristics, together with treatment administered and functional motor outcomes, were assessed.
Results
Among 61 …
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HL Teoh, SS Mohammad, PN Britton, T Kandula… - JAMA neurology, 2016