作者
Jonathan I Epstein, Mahul B Amin, Samson W Fine, Ferran Algaba, Manju Aron, Dilek E Baydar, Antonio Lopez Beltran, Fadi Brimo, John C Cheville, Maurizio Colecchia, Eva Comperat, Isabela Werneck da Cunha, Warick Delprado, Angelo M DeMarzo, Giovanna A Giannico, Jennifer B Gordetsky, Charles C Guo, Donna E Hansel, Michelle S Hirsch, Jiaoti Huang, Peter A Humphrey, Rafael E Jimenez, Francesca Khani, Qingnuan Kong, Oleksandr N Kryvenko, L Priya Kunju, Priti Lal, Mathieu Latour, Tamara Lotan, Fiona Maclean, Cristina Magi-Galluzzi, Rohit Mehra, Santosh Menon, Hiroshi Miyamoto, Rodolfo Montironi, George J Netto, Jane K Nguyen, Adeboye O Osunkoya, Anil Parwani, Brian D Robinson, Mark A Rubin, Rajal B Shah, Jeffrey S So, Hiroyuki Takahashi, Fabio Tavora, Maria S Tretiakova, Lawrence True, Sara E Wobker, Ximing J Yang, Ming Zhou, Debra L Zynger, Kiril Trpkov
发表日期
2021/4/1
来源
Archives of pathology & laboratory medicine
卷号
145
期号
4
页码范围
461-493
出版商
the College of American Pathologists
简介
Context
Controversies and uncertainty persist in prostate cancer grading.
Objective
To update grading recommendations.
Data Sources
Critical review of the literature along with pathology and clinician surveys.
Conclusions
Percent Gleason pattern 4 (%GP4) is as follows: (1) report %GP4 in needle biopsy with Grade Groups (GrGp) 2 and 3, and in needle biopsy on other parts (jars) of lower grade in cases with at least 1 part showing Gleason score (GS) 4 + 4 = 8; and (2) report %GP4: less than 5% or less than 10% and 10% increments thereafter. Tertiary grade patterns are as follows: (1) replace “tertiary grade pattern” in radical prostatectomy (RP) with “minor tertiary pattern 5 (TP5),” and only use in RP with GrGp 2 or 3 with less than 5% Gleason pattern 5; and (2) minor TP5 is noted along with the GS, with the GrGp based on the GS. Global …
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JI Epstein, MB Amin, SW Fine, F Algaba, M Aron… - Archives of pathology & laboratory medicine, 2021