作者
Patrick G McPhee, Jan Willem Gorter, Lisa M Cotie, Brian W Timmons, Todd Bentley, Maureen J MacDonald
发表日期
2015/12/1
期刊
Atherosclerosis
卷号
243
期号
2
页码范围
462-465
出版商
Elsevier
简介
Background
Persons with cerebral palsy (CP) have mobility limitations and may be at increased risk for cardiovascular disease (CVD).
Aims
To determine the feasibility of assessing novel CVD risk indicators and to identify predictors of CVD risk in a clinic-based group of adults with CP.
Methods
In an observational study, we examined 42 adults with CP (mean age 33.5 ± 12.3 yr). Traditional (resting blood pressure, smoking status and lipids) and novel CVD risk indicators (endothelial function, arterial stiffness, and carotid wall thickness) were assessed.
Results
Measures of endothelial function and central arterial stiffness were conducted in 100% and 83% of participants, respectively. Age was the strongest independent predictor of vascular health (cIMT, Age, R square = 0.576, p = 0.001).
Conclusion
Non-invasive measures of arterial structure and function are feasible to assess and may assist in the prediction of CVD …
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