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Policies and changes to the built environment are promising targets for obesity prevention efforts and can be evaluated as ‘natural'‐ or ‘quasi'‐experiments. This systematic review examined the use of natural‐ or quasi‐experiments to evaluate the efficacy of policy and built environment changes on obesity‐related outcomes (body mass index, diet or physical activity). PubMed (Medline) was searched for studies published 2005–2013; 1,175 abstracts and 115 papers were reviewed. Of the 37 studies included, 18 studies evaluated impacts on nutrition/diet, 17 on physical activity and 3 on body mass index. Nutrition‐related studies found greater effects because of bans/restrictions on unhealthy foods, mandates offering healthier foods, and altering purchase/payment rules on foods purchased using low‐income food vouchers compared with other interventions (menu labelling, new supermarkets). Physical activity …