作者
Shuo Wang, Oju Jeon, Peter G Shankles, Yuan Liu, Eben Alsberg, Scott T Retterer, Bruce P Lee, Chang Kyoung Choi
发表日期
2016/1/1
期刊
Biomicrofluidics
卷号
10
期号
1
出版商
AIP Publishing
简介
We present a simple microfluidic technique to in-situ photopolymerize (by 365 nm ultraviolet) monodisperse oxidized methacrylated alginate (OMA) microgels using a photoinitiator (VA-086). By this technique, we generated monodisperse spherical OMA beads and discoid non-spherical beads with better shape consistency than ionic crosslinking methods do. We found that a high monomer concentration (8 w/v%), a high photoinitiator concentration (1.5 w/v%), and absence of oxygen are critical factors to cure OMA microgels. This photopolymerizing method is an alternative to current methods to form alginate microgels and is a simpler approach to generate non-spherical alginate microgels.
引用总数
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