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The present study examined racial/ethnic differences in US drug overdose mortality among US-born and foreign-born men and women.

In this cross-sectional analysis of 2010–2019 data from the National Center for Health Statistics, Bayesian hierarchical models predicted drug overdose mortality based on the interaction of race/ethnicity, nativity, and sex, adjusting for age, for 518,553 drug overdose deaths among individuals ages 15–74 identified as Non-Hispanic (NH) White, NH Black, Hispanic, or NH Asian/Pacific Islander (PI). Rate ratios with 95% Highest Posterior Density Intervals (HPDIs) were examined by race/ethnicity and nativity.

In the US-born population, 2017–2019 estimated overdose mortality rates were higher for NH Black than NH White men (ratio 1.48 [95% HPDI 1.28–1.72]), similar between NH Black and NH White women (ratio 1.03 [95% HPDI 0.89–1.20]), similar …