作者
Dylan M Williams, Abigail Fraser, Debbie A Lawlor
发表日期
2011/2/15
期刊
Heart
卷号
97
期号
4
页码范围
315-320
出版商
BMJ Publishing Group Ltd
简介
Objective
To examine independent associations of serum 25-hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH) and calcium with a range of cardiovascular risk factors in adolescents.
Design
Cross-sectional population-based study.
Setting
A nationally representative sample of the US adolescent population.
Participants
Healthy adolescents (aged 12–19) participating in the National Health and Nutrition Examination Survey (NHANES) between 2001 and 2006. Numbers varied between 740 and 5609 for given exposure and outcome associations.
Main outcome measures
Systolic blood pressure (SBP), diastolic blood pressure (DBP), lipids (triglycerides, low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C)), fasting insulin and glucose, postload glucose and glycohaemoglobin (HbA1c).
Results
25(OH)D was inversely associated with SBP (−0.068 standard deviations (SD), 95 …
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DM Williams, A Fraser, DA Lawlor - Heart, 2011