作者
Sheng Chen, Jinqi Luo, Cesar Reis, Anatol Manaenko, Jianmin Zhang
发表日期
2017/10
来源
BioMed research international
卷号
2017
出版商
Hindawi
简介
Hydrocephalus (HCP) is a common complication in patients with subarachnoid hemorrhage. In this review, we summarize the advanced research on HCP and discuss the understanding of the molecular originators of HCP and the development of diagnoses and remedies of HCP after SAH. It has been reported that inflammation, apoptosis, autophagy, and oxidative stress are the important causes of HCP, and well‐known molecules including transforming growth factor, matrix metalloproteinases, and iron terminally lead to fibrosis and blockage of HCP. Potential medicines for HCP are still in preclinical status, and surgery is the most prevalent and efficient therapy, despite respective risks of different surgical methods, including lamina terminalis fenestration, ventricle‐peritoneal shunting, and lumbar‐peritoneal shunting. HCP remains an ailment that cannot be ignored and even with various solutions the medical …
引用总数
20172018201920202021202220232024514263245494016
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