作者
Nana Hyldig, H Birke-Sorensen, M Kruse, C Vinter, JS Joergensen, JA Sorensen, O Mogensen, RF Lamont, C Bille
发表日期
2016/4
来源
Journal of British Surgery
卷号
103
期号
5
页码范围
477-486
出版商
Oxford University Press
简介
Background
Postoperative wound complications are common following surgical procedures. Negative-pressure wound therapy (NPWT) is well recognized for the management of open wounds and has been applied recently to closed surgical incisions. The evidence base to support this intervention is limited. The aim of this study was to assess whether NPWT reduces postoperative wound complications when applied to closed surgical incisions.
Methods
This was a systematic review and meta-analysis of randomized clinical trials of NPWT compared with standard postoperative dressings on closed surgical incisions.
Results
Ten studies met the inclusion criteria, reporting on 1311 incisions in 1089 patients. NPWT was associated with a significant reduction in wound infection (relative risk (RR) 0·54, 95 per cent c.i. 0·33 to 0·89) and seroma formation (RR 0 …
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