作者
Peter Bager, Jan Wohlfahrt, Jannik Fonager, Morten Rasmussen, Mads Albertsen, Thomas Yssing Michaelsen, Camilla Holten Møller, Steen Ethelberg, Rebecca Legarth, Mia Sarah Fischer Button, Sophie Gubbels, Marianne Voldstedlund, Kåre Mølbak, Robert Leo Skov, Anders Fomsgaard, Tyra Grove Krause
发表日期
2021/11/1
期刊
The Lancet Infectious Diseases
卷号
21
期号
11
页码范围
1507-1517
出版商
Elsevier
简介
Background
The more infectious SARS-CoV-2 lineage B.1.1.7 rapidly spread in Europe after December, 2020, and a concern that B.1.1.7 could cause more severe disease has been raised. Taking advantage of Denmark's high RT-PCR testing and whole genome sequencing capacities, we used national health register data to assess the risk of COVID-19 hospitalisation in individuals infected with B.1.1.7 compared with those with other SARS-CoV-2 lineages.
Methods
We did an observational cohort study of all SARS-CoV-2-positive cases confirmed by RT-PCR in Denmark, sampled between Jan 1 and March 24, 2021, with 14 days of follow-up for COVID-19 hospitalisation. Cases were identified in the national COVID-19 surveillance system database, which includes data from the Danish Microbiology Database (RT-PCR test results), the Danish COVID-19 Genome Consortium, the National Patient Registry, the Civil …
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P Bager, J Wohlfahrt, J Fonager, M Rasmussen… - The Lancet Infectious Diseases, 2021