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The present study investigated whether face cooling reduced both the perceived exertion (RPE) and prolactin (PRL) release during hyperthermic exercise. Ten, non‐heat‐acclimated males (23 ± 2 years; maximal oxygen consumption, 56 ± 7 ml kg^–1 min^–1[mean ±s.d.]) exercised for 40 min on a cycle ergometer at 65% of their peak aerobic power, at an ambient temperature of 33°C (27% relative humidity) with (FC) and without face cooling as a control (CON). With FC, forehead temperature was maintained ∼6°C lower than CON, while other skin sites were similar or slightly warmer in the FC condition. Rectal temperature increased by ∼1.5°C with the same time course in both conditions. A relative bradycardia was observed during FC, with heart rate approximately 5 beats min^–1 lower than CON (P < 0.05). Mean plasma lactate was lower during FC (FC, 5.0 ± 0.3 mmol l^–1; CON, 5.9 ± 0.3 mmol l^–1; P < 0.05) but no …