作者
Mark O Wielpütz, Oyunbileg von Stackelberg, Mirjam Stahl, Bertram J Jobst, Monika Eichinger, Michael U Puderbach, Lutz Nährlich, Sandra Barth, Christian Schneider, Matthias V Kopp, Isabell Ricklefs, Michael Buchholz, Burkhard Tümmler, Christian Dopfer, Jens Vogel-Claussen, Hans-Ulrich Kauczor, Marcus A Mall
发表日期
2018/7/1
期刊
Journal of Cystic Fibrosis
卷号
17
期号
4
页码范围
518-527
出版商
Elsevier
简介
Background
A recent single-centre study demonstrated that MRI is sensitive to detect early abnormalities in the lung and response to therapy in infants and preschool children with cystic fibrosis (CF) supporting MRI as an outcome measure of early CF lung disease. However, the feasibility of multicentre standardisation remains unknown.
Objective
To determine the feasibility of multicentre standardisation of chest MRI in infants and preschool children with CF.
Methods
A standardised chest 1.5 T MRI protocol was implemented across four specialised CF centres. Following training and initiation visits, 42 infants and preschool children (mean age 3.2 ± 1.5 years, range 0–6 years) with clinically stable CF underwent MRI and chest X-ray (CXR). Image quality and lung abnormalities were assessed using a standardised questionnaire and an established CF MRI and CXR score.
Results
MRI was successfully performed with …
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MO Wielpütz, O von Stackelberg, M Stahl, BJ Jobst… - Journal of Cystic Fibrosis, 2018