作者
Shivam Singh, Kunal Khurana, Shikha Baghel Chauhan, Indu Singh
发表日期
2023/9/5
来源
Future Journal of Pharmaceutical Sciences
卷号
9
期号
1
页码范围
78
出版商
Springer Berlin Heidelberg
简介
Background
Emulsomes are a type of lipid-based nanoparticle that consists of a solid lipid core surrounded by a phospholipid bilayer and have shown promise as drug delivery systems for a variety of applications. The major advantageous aspect of employing lipid-based carriers is their ability to enhance the solubility and bioavailability of poorly water-soluble drugs, mandatorily in case of intranasal drug delivery. These structures have portrayed significant ability to encapsulate drug with poor water solubility and low oral bioavailability, further leading to a completely enhanced drug delivery systems for achieving stability and controlled release of drug. The selection of lipid components and their physiochemical properties can be tailored to optimize drug solubility, blood brain barrier permeability, and enhanced targeting.
Main body of abstract
Intranasal drug delivery systems offer several advantages over other routes …
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