作者
Rosalie C Viney, Michael J Boyer, Madeleine T King, Patricia M Kenny, Christine A Pollicino, Jocelyn M McLean, Brian C McCaughan, Michael J Fulham
发表日期
2004/6/15
期刊
Journal of Clinical Oncology
卷号
22
期号
12
页码范围
2357-2362
出版商
American Society of Clinical Oncology
简介
Purpose
Positron emission tomography (PET) is a costly new technology with potential to improve preoperative evaluation for patients with non–small-cell lung cancer (NSCLC). There is increasing pressure for PET to be included in standard diagnostic work-up before decisions about surgical management of NSCLC. The resource implications of its widespread use in staging NSCLC are significant.
Methods
A randomized controlled trial was conducted to investigate the impact of PET on clinical management and surgical outcomes for patients with stage I-II NSCLC. The primary hypothesis was that PET would reduce the proportion of patients with stage I-II NSCLC who underwent thoracotomy by at least 10% through identification of patients with inoperable disease.
Results
One hundred eighty-four patients with stage I-II NSCLC were recruited and randomly assigned; 92 …
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RC Viney, MJ Boyer, MT King, PM Kenny, CA Pollicino… - Journal of Clinical Oncology, 2004