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Please cite this paper as: Bonzini M, Palmer K, Coggon D, Carugno M, Cromi A, Ferrario M. Shift work and pregnancy outcomes: a systematic review with meta‐analysis of currently available epidemiological studies. BJOG 2011;118:1429–1437.

Background  Varying work schedules are suspected of increasing risks to pregnant women and to fetal wellbeing. In particular, maternal hormonal disturbance arising from sleep deprivation or circadian rhythm disruption might impair fetal growth or lead to complications of pregnancy. Two independent meta‐analyses (from 2000 to 2007) reported a small adverse effect of shift work on the risk of preterm delivery (PTD). However, these reviews were based on few high‐quality studies.

Objectives  To provide an updated review of the associations of shift work with PTD, low birthweight (LBW), small‐for‐gestational‐age (SGA) infants and pre‐eclampsia.

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