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BACKGROUND:

The standard treatment of resected brain metastasis is whole-brain radiotherapy (WBRT). To avoid the potential toxicity of WBRT and to improve local control, we have used radiosurgery alone to the surgical cavity.

OBJECTIVE:

To demonstrate the rates of local control, new intracranial metastasis, and overall survival using this treatment scheme without WBRT.

METHODS:

Eighty-five consecutive patients with brain metastasis were treated with surgical resection of at least 1 lesion followed by radiosurgery alone to the surgical cavity and any unresected lesions from August 2000 to March 2011. Sixty-eight percent had gross total resections. After surgery, radiosurgery was delivered to the surgical cavity with a 2-to 3-mm margin. The median marginal radiosurgery dose was 16 Gy, and median target volume was 13.96 cm 3. Follow-up imaging and clinical examination were obtained every 2 to 3 months …