作者
Sandrine Lablanche, Sophie Borot, Anne Wojtusciszyn, Francois Bayle, Rachel Tétaz, Lionel Badet, Charles Thivolet, Emmanuel Morelon, Luc Frimat, Alfred Penfornis, Laurence Kessler, Coralie Brault, Cyrille Colin, Igor Tauveron, Domenico Bosco, Thierry Berney, Pierre-Yves Benhamou, Gragil Network
发表日期
2015/9/1
期刊
Diabetes care
卷号
38
期号
9
页码范围
1714-1722
出版商
American Diabetes Association
简介
OBJECTIVE
To describe the 5-year outcomes of islet transplantation within the Swiss-French GRAGIL Network.
RESEARCH DESIGN AND METHODS
Retrospective analysis of all subjects enrolled in the GRAGIL-1c and GRAGIL-2 islet transplantation trials. Parameters related to metabolic control, graft function, and safety outcomes were studied.
RESULTS
Forty-four patients received islet transplantation (islet transplantation alone [ITA] 24 patients [54.5%], islet after kidney [IAK] transplantation 20 patients [45.5%]) between September 2003 and April 2010. Recipients received a total islet mass of 9,715.75 ± 3,444.40 IEQ/kg. Thirty-four patients completed a 5-year follow-up, and 10 patients completed a 4-year follow-up. At 1, 4, and 5 years after islet transplantation, respectively, 83%, 67%, and 58% of the ITA recipients and 80%, 70%, and 60% of the IAK …
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S Lablanche, S Borot, A Wojtusciszyn, F Bayle, R Tétaz… - Diabetes care, 2015