作者
SA Pileri, TM Grogan, NL Harris, P Banks, E Campo, JKC Chan, RD Favera, G Delsol, C De Wolf‐Peeters, Brunangelo Falini, Randy D Gascoyne, P Gaulard, KC Gatter, PG Isaacson, Elaine S Jaffe, P Kluin, DM Knowles, DY Mason, S Mori, H‐K Müller‐Hermelink, MA Piris, E Ralfkiaer, Harald Stein, I‐J Su, RA Warnke, LM Weiss
发表日期
2002/7
来源
Histopathology
卷号
41
期号
1
页码范围
1-29
出版商
Blackwell Science Ltd
简介
Tumours of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases
Neoplasms of histiocytes and dendritic cells are rare, and their phenotypic and biological definition is incomplete. Seeking to identify antigens detectable in paraffin‐embedded sections that might allow a more complete, rational immunophenotypic classification of histiocytic/dendritic cell neoplasms, the International Lymphoma Study Group (ILSG) stained 61 tumours of suspected histiocytic/dendritic cell type with a panel of 15 antibodies including those reactive with histiocytes (CD68, lysozyme (LYS)), Langerhans cells (CD1a), follicular dendritic cells (FDC: CD21, CD35) and S100 protein. This analysis revealed that 57 cases (93%) fit into four major immunophenotypic groups (one histiocytic and three dendritic cell types) utilizing six markers …
引用总数
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