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Several researchers have focussed on degradation of pesticides by microorganisms, which is the most viable option in remediation of agricultural soil. However, very few have illustrated the degradation of mixed pesticides. Hence, in the present investigation biodegradation of a mixture of both organophosphorus and organochlorine pesticide directed by microbial consortium was carried out in a fermentor–bioreactor system. The pesticides chosen were chlorpyrifos, monocrotophos (organophosphorus) and endosulfan (organochlorine). In order to accomplish an effective degradation, the microorganisms were isolated from agricultural fields which were previously exposed to the pesticides mentioned above. The bacteria were isolated by minimal meda with the individual pesticide as the only carbon source. The individual strains were identified by morphological, biochemical and 16S rRNA characterization. The …