作者
Nita G Forouhi, Albert Koulman, Stephen J Sharp, Fumiaki Imamura, Janine Kröger, Matthias B Schulze, Francesca L Crowe, José María Huerta, Marcela Guevara, Joline Wj Beulens, Geertruida J van Woudenbergh, Laura Wang, Keith Summerhill, Julian L Griffin, Edith Jm Feskens, Pilar Amiano, Heiner Boeing, Françoise Clavel-Chapelon, Laureen Dartois, Guy Fagherazzi, Paul W Franks, Carlos Gonzalez, Marianne Uhre Jakobsen, Rudolf Kaaks, Timothy J Key, Kay-Tee Khaw, Tilman Kühn, Amalia Mattiello, Peter M Nilsson, Kim Overvad, Valeria Pala, Domenico Palli, J Ramón Quirós, Olov Rolandsson, Nina Roswall, Carlotta Sacerdote, María-José Sánchez, Nadia Slimani, Annemieke Mw Spijkerman, Anne Tjonneland, Maria-José Tormo, Rosario Tumino, Yvonne T van der Schouw, Claudia Langenberg, Elio Riboli, Nicholas J Wareham
发表日期
2014/10/31
期刊
The Lancet Diabetes & Endocrinology
卷号
2
期号
10
页码范围
810-818
出版商
Elsevier
简介
Background
Conflicting evidence exists regarding the association between saturated fatty acids (SFAs) and type 2 diabetes. In this longitudinal case-cohort study, we aimed to investigate the prospective associations between objectively measured individual plasma phospholipid SFAs and incident type 2 diabetes in EPIC-InterAct participants.
Methods
The EPIC-InterAct case-cohort study includes 12 403 people with incident type 2 diabetes and a representative subcohort of 16 154 individuals who were selected from a cohort of 340 234 European participants with 3·99 million person-years of follow-up (the EPIC study). Incident type 2 diabetes was ascertained until Dec 31, 2007, by a review of several sources of evidence. Gas chromatography was used to measure the distribution of fatty acids in plasma phospholipids (mol%); samples from people with type 2 diabetes and subcohort participants were processed in …
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NG Forouhi, A Koulman, SJ Sharp, F Imamura… - The lancet Diabetes & endocrinology, 2014