作者
Chao Wang, Qiao Chen, Quanping Guo, Hong Liu, Zhaoqing Xu, Yubing Liu, Mengran Wang, Rui Wang
发表日期
2016/7/1
期刊
The Journal of Organic Chemistry
卷号
81
期号
13
页码范围
5782-5788
出版商
American Chemical Society
简介
A AgOAc catalyzed difunctionalization of activated alkenes through a difluoroamidic radical addition to afford difluoroamidated 3,3-disubstituted oxindoles has been developed. Various functional groups were well tolerated. Moreover, the product could be efficiently derived to the corresponding difluorofunctionalized alcohol, ketone, and ester in high yields. The mechanistic studies revealed that a radical pathway was involved in the transformation.
学术搜索中的文章
C Wang, Q Chen, Q Guo, H Liu, Z Xu, Y Liu, M Wang… - The Journal of Organic Chemistry, 2016