作者
Dale Roach, Lois C Holloway, Michael G Jameson, Jason A Dowling, Angel Kennedy, Peter B Greer, Michele Krawiec, Robba Rai, Jim Denham, Jeremiah De Leon, Karen Lim, Megan E Berry, Rohen T White, Sean A Bydder, Hendrick T Tan, Jeremy D Croker, Alycea McGrath, John Matthews, Robert J Smeenk, Martin A Ebert
发表日期
2019/4
期刊
Journal of medical imaging and radiation oncology
卷号
63
期号
2
页码范围
264-271
简介
Introduction
This study quantified inter‐observer contouring variations for multiple male pelvic structures, many of which are of emerging relevance for prostate cancer radiotherapy progression and toxicity response studies.
Methods
Five prostate cancer patient datasets (CT and T2‐weighted MR) were distributed to 13 observers for contouring. CT structures contoured included the clinical target volume (CTV), seminal vesicles, rectum, colon, bowel bag, bladder and peri‐rectal space (PRS). MR contours included CTV, trigone, membranous urethra, penile bulb, neurovascular bundle and multiple pelvic floor muscles. Contouring variations were assessed using the intraclass correlation coefficient (ICC), Dice similarity coefficient (DSC), and multiple additional metrics.
Results
Clinical target volume (CT and MR), bladder, rectum and PRS contours showed excellent inter‐observer agreement (median ICC = 0.97; 0 …
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D Roach, LC Holloway, MG Jameson, JA Dowling… - Journal of medical imaging and radiation oncology, 2019