作者
Myo Min, Mark T Lee, Peter Lin, Lois Holloway, Dj Wijesekera, Dinesh Gooneratne, Robba Rai, Wei Xuan, Allan Fowler, Dion Forstner, Gary Liney
发表日期
2016/2/1
期刊
The British journal of radiology
卷号
89
期号
1058
页码范围
20150530
出版商
The British Institute of Radiology.
简介
Objective
To evaluate the serial changes and correlations between readout-segmented technique with navigated phase correction diffusion-weighted MRI (DWI), R 2*-MRI and 18F-FDG positron emission tomography (PET) CT performed before and during radiation therapy (RT) in patients with mucosal primary head and neck cancer.
Methods
The mean apparent diffusion coefficient (ADCmean) from DWI (at b = 50 and 800 s mm−2), the mean R 2* values derived from T 2 *-MRI, and PET metabolic parameters, including maximum standardized uptake value (SUVmax), metabolic tumour volume (MTV) and total lesional glycolysis (TLG) were measured for the primary tumour. Spearman correlation coefficients were calculated to evaluate correlations between ADCmean, R 2*, SUVmax, MTV and TLG. A paired t-test was performed to assess the MRI changes and the slope of …
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M Min, MT Lee, P Lin, L Holloway, D Wijesekera… - The British journal of radiology, 2016