作者
Shun Kohsaka, Zhezhen Jin, Tatjana Rundek, Bernadette Boden-Albala, Shunichi Homma, Ralph L Sacco, Marco R Di Tullio
发表日期
2008/9
期刊
JACC: Cardiovascular Imaging
卷号
1
期号
5
页码范围
617-623
出版商
American College of Cardiology Foundation
简介
Objectives
We sought to determine the magnitude of the association between mitral annular calcification (MAC) and vascular events in a multiethnic cohort.
Background
Mitral annular calcification is common in the elderly and is associated with atherosclerotic risk factors. Its impact on the risk of cardiovascular events is controversial.
Methods
The study cohort consisted of 1,955 subjects, ages ≥40 years, and free of prior myocardial infarction (MI) and ischemic stroke (IS). Mitral annular calcification was assessed by transthoracic 2-dimensional echocardiography. The association between MAC and MI, IS, and vascular death (VD) was examined by Cox proportional hazard models with adjustment for established cardiovascular risk factors. The effect of MAC thickness was also analyzed.
Results
The mean age of the cohort was 68.0 ± 9.7 years and the majority of subjects were Hispanics (56.8%). A total of 519 subjects …
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S Kohsaka, Z Jin, T Rundek, B Boden-Albala… - JACC: Cardiovascular Imaging, 2008