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The aim of the present review is to summarize the current state of research in the field of sustainable bio-based adhesives used for production of eco-friendly wood composite materials. The article is focused mainly on the use of lignin, starch and tannins as raw materials and alternatives to the existing conventional adhesives. It is expected that increased amounts of biobased adhesives will be used in the production of wood composites in order to meet the current needs for development of sustainable and innovative materials which will make the wood-based panel industry more sustainable and lower its dependence on fossil fuels. However, there are still substantial challenges for the complete replacement of petroleum-based wood adhesives with biobased adhesives, mainly because of their relatively poor water resistance, low bonding strength and large natural variations due to different growing conditions. In this respect, fundamental research is still need in order to determine the factors for formulating bio-based adhesives with optimal properties and broaden their application in wood-based panel industry.