作者
Daniele Roberto Giacobbe, Alberto Enrico Maraolo, Vittorio Simeon, Federica Magnè, Maria Caterina Pace, Ivan Gentile, Paolo Chiodini, Claudio Viscoli, Maurizio Sanguinetti, Malgorzata Mikulska, Marco Fiore, Matteo Bassetti
发表日期
2020/4
来源
Mycoses
卷号
63
期号
4
页码范围
334-342
简介
Background
Candidaemia remains associated with high mortality and increased costs worldwide.
Objective
To assess the changes over time in the relative prevalence of non‐albicans candidaemia (NAC).
Methods
A systematic review, meta‐analysis and meta‐regression were performed. Observational studies investigating the epidemiology of consecutive, non‐selected, candidaemia episodes were included. Two separated analyses were conducted: (a) whole hospital analysis and (b) intensive care unit (ICU) analysis.
Results
Starting from an initial total of 7726 records, 220 studies fulfilled inclusion criteria. The pooled prevalence of NAC in whole hospital analysis was 49.5% (95% confidence intervals [CI] 48.0‐51.1, I2 93.1%), while the pooled prevalence in ICU analysis was 50.6% (95% CI 46.6‐54.6; I2 86.7%). In meta‐regression, a progressive increase in NAC prevalence was observed in whole hospital …
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DR Giacobbe, AE Maraolo, V Simeon, F Magnè… - Mycoses, 2020