作者
Julie Bennett, Nicole J Moreland, Jane Zhang, Julian Crane, Dianne Sika-Paotonu, Jonathan Carapetis, Deborah A Williamson, Michael G Baker
发表日期
2022/9/1
期刊
The Lancet Regional Health–Western Pacific
卷号
26
出版商
Elsevier
简介
Background
Group A streptococcal (GAS) infections can trigger an immune-mediated response resulting in acute rheumatic fever (ARF). The role of social and environmental risk factors for GAS pharyngitis and skin infections are not well understood. This study aimed to identify factors associated with GAS pharyngitis and skin infections, and to determine if these are the same as those for ARF.
Methods
A case-control study, including 733 children aged 5-14 years, was undertaken between March 2018 and October 2019 in Auckland, New Zealand. Healthy controls (n = 190) and symptomatic cases including GAS pharyngitis (n = 210), GAS seronegative carriers (n = 182), and GAS skin infections (n = 151) were recruited. Trained interviewers administered a comprehensive, pre-tested, face-to-face questionnaire.
Findings
Multivariable analysis identified strong associations between barriers to accessing primary …
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