作者
Antoine Diez, Andrew L Krause, Philip K Maini, Eamonn A Gaffney, Sungrim Seirin-Lee
发表日期
2024/2
期刊
Bulletin of Mathematical Biology
卷号
86
期号
2
页码范围
13
出版商
Springer US
简介
Conditions for self-organisation via Turing’s mechanism in biological systems represented by reaction-diffusion or reaction-cross-diffusion models have been extensively studied. Nonetheless, the impact of tissue stratification in such systems is under-explored, despite its ubiquity in the context of a thin epithelium overlying connective tissue, for instance the epidermis and underlying dermal mesenchyme of embryonic skin. In particular, each layer can be subject to extensively different biochemical reactions and transport processes, with chemotaxis - a special case of cross-diffusion - often present in the mesenchyme, contrasting the solely molecular transport typically found in the epidermal layer. We study Turing patterning conditions for a class of reaction-cross-diffusion systems in bilayered regions, with a thin upper layer and coupled by a linear transport law. In particular, the role of differential transport through the …
学术搜索中的文章
A Diez, AL Krause, PK Maini, EA Gaffney, S Seirin-Lee - Bulletin of Mathematical Biology, 2024