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5G network slicing is essential to providing flexible, scalable, and on-demand solutions for the vast array of applications in 5G networks. Two key challenges of 5G network slicing are function isolation (intra-slice) and guaranteeing end-to-end delay for a slice. In this letter, we address the question of optimal allocation of a slice in 5G core networks by tackling these two challenges. We adopt and extend the work by Dietrich et al. (see introduction) to create a model that satisfies constraints on end-to-end delay as well as isolation between components of a slice for reliability.