作者
Kerstin Klaser, Ellen J Thompson, Long H Nguyen, Carole H Sudre, Michela Antonelli, Benjamin Murray, Liane S Canas, Erika Molteni, Mark S Graham, Eric Kerfoot, Liyuan Chen, Jie Deng, Anna May, Christina Hu, Andy Guest, Somesh Selvachandran, David A Drew, Marc Modat, Andrew T Chan, Jonathan Wolf, Tim D Spector, Alexander Hammers, Emma L Duncan, Sebastien Ourselin, Claire J Steves
发表日期
2021/12/1
期刊
Journal of Neurology, Neurosurgery & Psychiatry
卷号
92
期号
12
页码范围
1254-1258
出版商
BMJ Publishing Group Ltd
简介
Background
Mental health issues have been reported after SARS-CoV-2 infection. However, comparison to prevalence in uninfected individuals and contribution from common risk factors (eg, obesity and comorbidities) have not been examined. We identified how COVID-19 relates to mental health in the large community-based COVID Symptom Study.
Methods
We assessed anxiety and depression symptoms using two validated questionnaires in 413148 individuals between February and April 2021; 26998 had tested positive for SARS-CoV-2. We adjusted for physical and mental prepandemic comorbidities, body mass index (BMI), age and sex.
Findings
Overall, 26.4% of participants met screening criteria for general anxiety and depression. Anxiety and depression were slightly more prevalent in previously SARS-CoV-2-positive (30.4%) vs SARS-CoV-2-negative (26.1%) individuals. This association was small …
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K Klaser, EJ Thompson, LH Nguyen, CH Sudre… - Journal of Neurology, Neurosurgery & Psychiatry, 2021