作者
Maysa Paula da Costa, Marize Campos Valadares Bozinis, Wanessa Machado Andrade, Carolina Rodrigues Costa, Alessandro Lopes da Silva, Cecília Maria Alves de Oliveira, Lucília Kato, Orionalda de Fátima Lisboa Fernandes, Lúcia Kioko Hasimoto Souza, Maria do Rosário Rodrigues Silva
发表日期
2014/12
期刊
BMC complementary and alternative medicine
卷号
14
页码范围
1-7
出版商
BioMed Central
简介
Background
The great potential of plants as Hymenaea courbaril L (jatoba) has not yet been throughly explored scientifically and therefore it is very important to investigate their pharmacological and toxicological activities to establish their real efficacy and safety. This study investigated the cytotoxicity of xylem sap of Hymenaea courbaril L and its bioactivity against the fungi Cryptococcus neoformans species complex and dermatophytes.
Methods
The fresh xylem sap of H. courbaril was filtered resulting in an insoluble brown color precipitate and was identified as fisetin. In the filtrate was identified the mixture of fisetinediol, fustin, 3-O-methyl-2,3-trans-fustin and taxifolin, which were evaluated by broth microdilution antifungal susceptibility testing against C. neoformans species complex and dermatophytes. The fresh xylem sap and fisetin were screened for …
学术搜索中的文章
MP da Costa, MCV Bozinis, WM Andrade, CR Costa… - BMC complementary and alternative medicine, 2014