作者
Linsay McCallum, Stefanie Lip, Francisco J Rios, Karla B Neves, Jason Kilmartin, Eleanor Murray, Salil Reetoo, Laura Knox, Maggie Rostron, Angela Lucas-Herald, Clea Du Toit, Tomasz J Guzik, Christian Delles, Augusto C Montezano, Anna F Dominiczak, Sandosh Padmanabhan, Rhian M Touyz
发表日期
2021/9
期刊
Hypertension
卷号
78
期号
suppl_1
页码范围
AP265-AP265
出版商
Lippincott Williams & Wilkins
简介
Hypertension, vascular dysfunction and downregulation of the renin angiotensin system as sequelae of COVID-19
The long-term CV consequences of COVID are unknown however the potential for ongoing cardiac and vascular inflammation with RAAS alteration may increase the risk of developing hypertension and CV disease. Non-hypertensive patients hospitalised in April-May 2020 with either confirmed COVID19 (cases) or non-COVID (controls) diagnosis were recruited ≥12 weeks post-discharge. All underwent detailed BP and vascular/immune and RAAS phenotyping. The primary outcome was ABPM 24-hr SBP. Paired t-tests and multivariable regression models used to assess differences. Thirty cases and eighteen controls completed the study. Cases were older (51±7 vs 45±9 years) with lower discharge SBP (121±10 vs 128±15 mmHg; p0.01). ABPM at study visit was higher in the cases compared to …
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L McCallum, S Lip, FJ Rios, KB Neves, J Kilmartin… - Hypertension, 2021