作者
Kokilambigai K S, Seetharaman R., Kavitha J., Sowndaravel P, Lakshmi K. S
发表日期
2017
期刊
Journal of Pharmaceutical Sciences and Research
卷号
9
期号
6
页码范围
824-829
出版商
PharmaInfo Publications
简介
The present study focuses on the development and validation of a rapid, sensitive and precise multivariate calibration technique employing UV spectrophotometric method. Multivariate calibration method utilizes the linear regression equations by correlating the relation between concentration and absorbance at five different wavelengths. The results were treated statistically. The developed method was validated as per the ICH guidelines and was found to be accurate, precise and reproducible. The method is accurate, precise and linear within the range 8-12 µg/mL. This statistical approach gives optimum results by eliminating the fluctuations arising from the instrumental or experimental conditions.
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