作者
Fabiana Zingone, Joe West, Colin J Crooks, Kate M Fleming, Timothy R Card, Carolina Ciacci, Laila J Tata
发表日期
2015/5/1
期刊
Archives of disease in childhood
卷号
100
期号
5
页码范围
466-473
出版商
BMJ Publishing Group Ltd
简介
Background
Serological studies indicate that evidence of coeliac disease (CD) exists in about 1% of all children, but we lack estimates of current diagnostic patterns among children and how they vary by socioeconomic group.
Methods
We identified all children aged 0–18 years between 1993 and 2012 who were registered with general practices across the UK that contribute to a large population-based general practice database. The incidence of CD was evaluated in each quintile of the Townsend index of deprivation and stratified by age, sex, country and calendar year.
Results
Among 2 063 421 children, we identified 1247 CD diagnoses, corresponding to an overall CD incidence of 11.9 per 100 000 person-years, which was similar across the UK countries and higher in girls than in boys. We found a gradient of CD diagnosis across socioeconomic groups, with the rate of diagnosis being 80% higher in …
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F Zingone, J West, CJ Crooks, KM Fleming, TR Card… - Archives of disease in childhood, 2015