作者
Gianluca Serafini, Maurizio Pompili, Marco Innamorati, Paolo Fusar-Poli, Hagop S Akiskal, Zoltan Rihmer, David Lester, Andrea Romano, Irismar Reis de Oliveira, Leonardo Strusi, Stefano Ferracuti, Paolo Girardi, Roberto Tatarelli
发表日期
2011/3/1
期刊
Journal of affective disorders
卷号
129
期号
1-3
页码范围
47-55
出版商
Elsevier
简介
BACKGROUND
Patients with white matter hyperintensities (WMH) may be at higher risk for affective disorders and suicide. Affective temperaments may play a significant role in mood disorders. This study aimed to evaluate the eventual association between WMH, affective temperaments and suicidal behaviour in major affective disorder.
METHODS
A total of 318 patients with major affective disorders were consecutively admitted as psychiatric inpatient. A total of 247 were included and given, brain magnetic resonance imaging (MRI) and assessed with the Mini International Neuropsychiatric Interview (MINI), the Beck Hopelessness Scale (BHS), the Hamilton Depression Rating Scale (HDRS17), the Young Mania Rating Scale (YMRS) and the Temperament Evaluation of Memphis, Pisa, Paris and San Diego (TEMPS-A).
RESULTS
A total of 48% of patients had periventricular WMH (PWMH) and 39% of them had …
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