作者
Jose Cassio de Moraes, Brigina Kemp, Ana Paula Silva de Lemos, Maria Cecilia Outeiro Gorla, Eneida Gonçalves Lemes Marques, Maria do Carmo Ferreira, Claudio Sacchi, Telma Regina Marques Pinto Carvalhanas, Ana Freitas Ribeiro, Cleide Marques Ferreira, Maristela Marques Salgado, Lucila Fukasawa, Maria Gisele Gonçalves, Fabio Higa, Rodrigo Angerami, André Ribas Freitas, Helena Keico Sato, Marco Aurélio Palazzi Sáfadi
发表日期
2015/11/1
期刊
The Pediatric infectious disease journal
卷号
34
期号
11
页码范围
1197-1202
出版商
LWW
简介
Background:
In 2010, introduction of the meningococcal C conjugate vaccine in Brazil for children< 2 years provided an immediate reduction in the incidence rates of disease among the age groups targeted for the vaccine, but no early impact was observed in unvaccinated age groups. Knowledge about meningococcal carriage is crucial for improving our understanding of the disease epidemiology and for designing effective vaccination programs. Taking in account the very limited published data currently available describing meningococcal carriage in Brazil, we performed a study to evaluate the prevalence of Neisseria meningitidis carriage among adolescent students.
Methods:
A cross-sectional study was conducted in 2012 to assess the prevalence of meningococcal carriage among a representative sample of 1208 students 11–19 years of age in Campinas, Brazil. Genotypic and phenotypic characterization of …
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