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Patterns of genetic diversity across the genome are affected by multiple forces of evolution, including natural selection and population demography. These effects are manifested both locally across the genome and genome-wide. While natural selection operates directly on only a small percentage of mutations within genome, it can have wide effects across neutral regions due to genetic linkage. In the context of purifying selection at linked sites, this process is called'background selection'(BGS) and it leads to decreases in genetic diversity and skews the distribution of allele frequencies in the genome. While much theoretical and empirical investigation has gone into how BGS and demography operate independently to affect the genome, little investigation has been conducted on how these forces pattern the genome in concert. Utilizing thousands of human genomes and population genetic simulations, I have …