作者
Neda Nayebi, Alireza Esteghamati, Alipasha Meysamie, Nahid Khalili, Mohammad Kamalinejad, Majid Emtiazy, Mohammad Hashem Hashempur
发表日期
2019/8/27
期刊
Journal of Complementary and Integrative Medicine
卷号
16
期号
3
页码范围
20180088
出版商
De Gruyter
简介
Background
Diabetic patients are at increased risk for coronary artery disease. Since phytotherapy has been greatly common, finding safe and effective treatments is of importance. This study aimed to evaluate the effects of a Melissa officinalis L. based product (MO) in patients with type 2 diabetes.
Methods
A randomized double-blinded controlled study was conducted with 37 dyslipidemic diabetic patients, assigned to either MO or placebo (P) groups receiving two 500 mg capsules daily for 3 months. Finally, 32 cases completed the study and were included in the analysis; MO (n=16) and P (n=16).
Results
Safe and significant effects in terms of decreasing the serum level of triglyceride (TG) in all patients after 2 months (p-value=0.02) and in patients with higher baseline serum levels of TG (TG≥200 mg/dl) after 3 months (p-value=0.04) were shown in the MO group. However, no metabolic significant changes were …
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N Nayebi, A Esteghamati, A Meysamie, N Khalili… - Journal of Complementary and Integrative Medicine, 2019